First described by philipsen in 1956, the odontogenic keratocyst is characterized by a large squamous keratinization of its border, an aggressive growth and a high recurrent rate. Keratocystic odontogenic tumour an overview sciencedirect. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. Partial mandibulectomy rehabilitation of keratocystic odontogenic tumour case in neutral zone. Keratocystic odontogenic tumour kcot is a benign intraosseous neoplasm which can occur in a unicystic or multicystic form and originate from odontogenic tissue 1. Okcs arise from the dental lamina and are characterised by a cystic space containing desquamated keratin with a. Keratocystic odontogenic tumour kcot, traditionally known as odontogenic keratocyst, received its new title as kcot by the world health organisation who in order to emphasise its neoplastic biological nature. Teeth examination revealed that teeth 22 and 23 are missing, and teeth 21 and 24 are positive at cold sensitivity test without mobility. Therefore, odontogenic keratocysts okcs are now considered benign cysts of odontogenic origin that account for about 10% of all odontogenic cysts.
A keratocystic odontogenic tumour kcot occurring in the maxillary sinus is very often misdiagnosed to be a dentigerous cyst. Lewis key points computed tomography can be highly specific in the diagnosis of mandibular masses given an organized approach that considers both odontogenic and nonodontogenic tumors and cysts. Keywords keratocystic odontogenic tumour kcot, benign tumor, recurrence, treatment. There are many types of cysts of the jaws, but what makes the odontogenic keratocyst unusual are its characteristic histopathological and clinical features, including potentially aggressive behaviour, high recurrence rate, and an association with the nevoid basal cell carcinoma syndrome. Keratocystic odontogenic tumour kcot misdiagnosed as a. Okc is now referred to by the world health organization who as a keratocystic odontogenic tumour kcot, and who defined it as a benign uni or multicystic, intraosseous tumour of odontogenic origin, with a characteristic lining of parakeratinized stratified squamous epithelium. The authors conducted a search in english literature using the following keywords. Chapter 21 odontogenic and non odontogenic tumors of the jaws introduction. The bone stains heavily and peripheral ostectomy is possible that will remove any residual peripheral neoplastic tissue. The odontogenic keratocyst can be defined as a cystic benign tumor, being localized at the level of the mandible or the maxilla. The latest 4th edition of the world health organization who classification of head and neck tumours, published in january 2017, has reclassified keratocystic odontogenic tumour as odontogenic keratocyst.
It was formerly known as odontogenic keratocyst okc. Dec 11, 2018 jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. Adenomatoid odontogenic tumor keratocystic odontogenic tumour. Longterm observation of a large keratocystic odontogenic tumour of. Treatment of the keratocystic odontogenic tumor kcot in. It is now designated by the world health organization as a keratocystic odontogenic tumour kot. The keratocystic odontogenic tumor oral and maxillofacial surgery. Jaw tumors and cysts symptoms and causes mayo clinic. Odontogenic keratocyst and keratocystic odontogenic tumour. Keratocystic odontogenic tumour definition of keratocystic.
Kcot characterized by aggressive in nature and high recurrence rate. Jan 29, 2020 mandibular adenomatoid odontogenic tumor. Treatment consisted of enucleation and curettage for 22 of the lesions, resection for 2 and marsupialization for 3. Odontogenic keratocyst symptoms, treatment, pictures. Apr, 2016 odontogenic keratocyst or keratocystic odontogengic tumor. The odontogenic keratocyst, now officially known as the keratocystic odontogenic tumour kcot is an intraosseous tumor characterized by distinctive histopathologic findings.
Keratocystic odontogenic tumour masquerading as a mucosal. Reclassification and treatment of odontogenic keratocysts scielo. Keratocystic odontogenic tumours are known for their peculiar behaviour, varied origin, debated development, unique tendency to recur and disputed treatment modalities. Keratocystic odontogenic tumour canadian dental association.
The parakeratinized subtype became the keratocystic odontogenic tumor kcot, which integrated the group of odontogenic epithelial tumors into its. There were 18 lesions in the posterior mandible, 3 in the anterior mandible and 6 in the posterior maxilla fig. It was introduced by philipsen in 1956 for the first time. A keratocyst in the buccal mucosa with the features of keratocystic. January 2017, has reclassified keratocystic odontogenic tumour as odontogenic keratocyst. Introduction the frequency of odontogenic cysts in children is relatively low. Use of methylene blue for precise peripheral ostectomy of keratocystic odontogenic tumour after the tumour has been enucleated, the surface of the bone cavity is dyed with a 1% solution of methylene blue. In the whoiarc classification of head and neck pathology, this clinical entity had been known for years as the odontogenic keratocyst.
These growths are usually noncancerous benign, but they can be aggressive and invade the surrounding bone. Surgical management of dentigerous cyst and keratocystic. Adenomatoid, keratocystic, gorlingoltz, odontogenic tumours. Surgical treatment of keratocystic odontogenic tumour. Among the pathological entities that affect the maxillofacial region, keratocystic odontogenic tumour has been subject to a lot of debates. Odontogenic keratocyst is a distinctive form of developmental odontogenic cyst because of its specific histopathologic features, an aggressive biologic behavior and a high recurrence rate. Nov 10, 2009 the keratocystic odontogenic tumor is a benign developmental tumor with many distinguishing clinical and histologic features. Treatment consisted of enucleation and curettage for 22 of the lesions, resection. Current concepts, theory and presentation of 2 contrasting cases. Keratocystic odontogenic tumours kcots are benign lesions of the jaw that are characterised by expansive growth and high rates of recurrence. Thus, it has been the subject of much research over the last 40 years. In 2005, the world health organization who working group considered odontogenic keratocyst okc to be a tumor and recommended the term kcot.
Recurrence probability for keratocystic odontogenic tumors. Before i get started, let me say that in 2005, the world health organization actually changed the name of odontogenic keratocyst to keratocystic odontogenic tumor. A 14yearold caucasian girl presented for observation of bilateral agenesis. Cystic lesions should be examined cautiously to render appropriate treatment or else chances of recurrence of an aggressive lesion like the kcot are high.
Keratocystic odontogenic tumor in the maxillary sinus. Okc received its new title as keratocystic odontogenic tumour kcot by the who 2005 in order to suggest its aggressive and recurrent nature. A large extragnathic keratocystic odontogenic tumour a large extragnathic keratocystic odontogenic tumour. Diagnosing the most common odontogenic cystic and osseous.
Keratocystic odontogenic tumor kcot presents most frequently in the second, third and fourth decades of life 54. Odontogenic keratocyst okc is a developmental cyst that was first described by philipsen 1956. Albodbai mh 21 keratocystic odontogenic tumor in the maxillary sinus. Treatment options for keratocyst odontogenic tumour kcot. Odontogenic keratocysts make up around 19% of jaw cysts. There are many types of cysts of the jaws, but what makes the odontogenic keratocyst unusual are its characteristic histopathological and clinical features, including potentially aggressive behaviour, high recurrence rate, and an association with the nevoid basal cell carcinoma. Ive gotten a few questions about odontogenic keratocysts lately, so i figured it would be good to write an article detailing what we know about them. Okc received its new title as keratocystic odontogenic tumour kcot by the who 2005 in order to. We analyzed the etiopathogenetic, clinical, radiographic, and histopathologic aspects of keratocystic odontogenic tumors, particularly in association with dental anomalies of number, with the aim of providing useful information for their correct diagnosis, treatment, and prognosis within a multidisciplinary approach. Abstract the purpose of this paper is to focus the hallmarks of the keratocystic odontogenic tumour kcot which was formerly known as odontogenic keratocyst okc. Also known as the keratocystic odontic tumor, it is believed to be stemming from the dental lamina. Odontogenic and non odontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance.
The orthokeratinizing odontogenic cyst is considered an unrelated entity without risk of recurrence or aggressive growth or association with nevoid basal cell carcinoma syndrome. In recent studies a somatic mutation of ptch gene in some. Keratocystic odontogenic tumor gorlin syndrome alliance. A keratocystic odontogenic tumor kot formerly known as an odontogenic keratocyst is a benign cystic tumor of dental origin that probably arises from primitive dental lamina, most commonly occurs in the posterior mandible, and almost certainly represents the lesion that used to be known as a primordial cyst. Involvement of the maxillary sinus is an unusual presentation. Clinically, the kot is manifested by an asymptomatic growth. Keratocystic odontogenic tumor is not the most common of odontogenic cysts but it is an extremely important one for the pathologist to recognize. Pdf on may 1, 2014, madhumati amritraj singh and others published keratocystic odontogenic tumor find, read and cite all the research.
A large extragnathic keratocystic odontogenic tumour pdf. Pdf on may 1, 2014, madhumati amritraj singh and others published keratocystic odontogenic tumor find, read and cite all the research you need on researchgate. Review of the literature and report of a rare case. It is characterized by its fast aggressive growth and high risk of recurrence. Jaw tumors and cysts, sometimes called odontogenic tumors and cysts, can vary greatly in size and severity. Each of these main signs may be present alone or be associated to the other ones. Presentation of a keratocystic odontogenic tumor with. Investigation of clinicopathological parameters alongside. The latest 4th edition of the world health organization who classification of head and neck tumours, published in january 2017, has reclassified keratocystic odontogenic tumour as odontogenic. This condition is often encountered in young patients, who are in their 2nd or 3rd decade of life.
Pdf keratocystic odontogenic tumor kcot has been identified as a tumor after observation of its biological behavior and genetic abnormalities. Surgical treatment of odontogenic keratocyst tumour. Simultaneous adenomatoid odontogenic and keratocystic. Furthermore, secondary signs can be observed asides from the main ones. Kcots comprise approximately 11% of all cysts in the maxillofacial region and due to unspecific clinical and radiographic features, it can be misdiagnosed. The odontogenic keratocyst is a very well known odontogenic cyst. The keratocysticodontogenic tumour kcot is a developmental odontogenic cyst that originates from epithelial rests of dental lamina. The newly acknowledged neoplastic potential and its implications for treatment strategies are also discussed. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Organization who as a keratocystic odonto genic tumour kcot and is defined as a. Case report keratocystic odontogenic tumor simulating lateral. The term odontogenic keratocyst was first used by philipsen in 1956. Keratocystic odontogenic tumour of lesions treated in our clinic. Keratocystic odontogenic tumor kcot is one of the most common odontogenic tumors of ectodermal origin.
1479 20 461 994 909 68 127 982 465 763 1002 880 970 678 159 1101 1497 1179 565 1264 1482 248 1474 1397 693 879 824 340 1240 354 1277 811 1431 604 1031 563